Plant protection


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Biological fungicide


  • Bacillus subtilis  BSF4 0.3 g
  • CFU/g of formulation 1 × 109
  • Coformulants/inert substances q.s. to  100 g


Bacillus subtilis is a bacterium which exerts a preventive activity to eliminate or minimise attacks of parasitic fungi, through mechanisms of competition that deprive the pathogenic microorganisms of nutritional substances and space, thereby inhibiting their germination.

The BSF4 preparation has shown clear effectiveness in the containment of attacks by Bacterial fire blight (Erwinia amylovora) of pear, when applied during the periods of greatest crop susceptibility (e.g. flowering).

In addition, the BSF4 preparation has been found to be active in the containment of other fungal diseases.



Bacterial fire blight

Pear, apple


Strawberry, tomato, flowers-ornamental plants

Downy mildew

Tomato, lettuce, flowers-ornamental plants

Bacillus subtilis strain BSF4 occurs in nature and is not genetically modified, it is not toxic to humans or animals, and does not have any harmful effects on the environment.

The BSF4 formulation is suitable as part of an organic farming or integrated crop protection strategy because, due to the absence of a pre-harvest interval, the preparation can be used for treatments even close to harvest time.

The BSF4 formulation, stored at room temperature in the original packaging, remains stable for 18 months.

Recommended amounts

The BSF4 formulation is used in a concentration of 100-150 g/hl of spraying solution.

Method of Application

Apply as a preventive treatment in the presence of conditions favourable to development of the disease, or when the first signs of infection appear. In the specific case of fire blight, carry out the treatments:

  • during flowering (at least three applications)
  • within the 24 hours following any potentially infectious event
  • immediately prior to any potentially infectious event (where possible)

It is recommended to mix BSF4 solution with amino-acid based products (hydrolysed protein or seaweed) to enhance the vitality of the antagonist on the leaves and fruits. It is not advisable to apply the product during the hottest and sunniest hours of the day, due to the inhibitory action of UV rays.